In the densest parts of clusters the morphological mix and colors of galaxies is very different from galaxy properties in lower density regions. More recent evidence indicates that these properties change very smoothly from the cluster core out to several megaparsecs. I will focus on the fate of the gas in galaxies in these environments. When and where do galaxies stop accreting gas, how do they loose the gaseous reservoir, when does star formation stop? I will argue that it is the assembly of clusters that may affect the evolution of the galaxies.