The southernmost section of the San Andreas fault (SAF) in California has not produced a major earthquake in historic time (over more than 300 years), and is currently believed to be in the late phase of interseismic loading. Geologic and geodetic observations indicate that a significant fraction of the southern SAF is undergoing some creep. The extent of fault creep is largely unknown, but is clearly important for evaluating interseismic accumulation of the elastic strain energy. The slip rate on the southern SAF is also a subject of some debate, with estimates ranging from as low as ~10 mm/yr to as high as ~30 mm/yr. If the slip rate is high (~30 mm/yr), the slip deficit accrued on the southern SAF is of the order of 7-10 meters, close to, or in excess of a maximum interseismic deficit, as well as a co-seismic offset ever documented on the fault. I will review recent space geodetic data collected using Interferometric Synthetic Aperture Radar (InSAR) and Global Positioning System (GPS) on major plate boundary faults in southern California. The data indicate that both the southern San Andreas and San Jacinto faults are accumulating elastic strain at a relatively high rate (effective slip rates of 25 and 20 mm/yr, respectively). Both faults are also associated with a pronounced asymmetry in strain rate across the surface fault trace, with higher strain rates on the eastern side of the faults. I will discuss possible causes and implications from the inferred strain asymmetry, as well as the role of creep in the overall strain budget.