The region of the Galactic center contains several sources which demonstrate their activity at various wavelengths and particularly above several hundred keV. Escape of positrons from such a source or several sources into the interstellar medium, where they slow down and annihilate, can account for the 511 keV narrow line observed from this direction. 1E 1740.7-2942 object has been proposed as the most likely candidate to be responsible for this variable source of positrons. Besides, Nova Muscae shows a spectrum which is consistent with Comptonization by a thermal plasma kTe<=100 keV in its hard X-ray part, while a relatively narrow annihilation line observed by SIGMA on Jan. 20-21, 1991 implies that positrons annihilate in a much colder medium. We estimate the electron number density and the size of the emitting regions suggesting that annihilation features observed by SIGMA from Nova Muscae and 1E 1740.7-2942 are due to the positron slowing down and annihilation in thermal plasma. We show that in the case of Nova Muscae the observed radiation is coming from a pair plasma stream (ne+~ ne-) rather than from a gas cloud. We argue that two models are probably relevant to the 1E source: annihilation in (hydrogen) plasma ne+<=ne- at rest, and annihilation in the pair plasma stream, which involves matter from the source environment.